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Effect on walking distance and atherosclerosis progression of a nitric oxide-donating agent in intermittent claudication  Paolo Gresele, MD, PhD, Rino.

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Presentation on theme: "Effect on walking distance and atherosclerosis progression of a nitric oxide-donating agent in intermittent claudication  Paolo Gresele, MD, PhD, Rino."— Presentation transcript:

1 Effect on walking distance and atherosclerosis progression of a nitric oxide-donating agent in intermittent claudication  Paolo Gresele, MD, PhD, Rino Migliacci, MD, PhD, Enrico Arosio, MD, Erminio Bonizzoni, PhD, Pietro Minuz, MD, Francesco Violi, MD  Journal of Vascular Surgery  Volume 56, Issue 6, Pages e5 (December 2012) DOI: /j.jvs Copyright © 2012 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Flow chart of the trial profile. ITT, Intention to treat; OT, on-treatment. Journal of Vascular Surgery  , e5DOI: ( /j.jvs ) Copyright © 2012 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Evolution of the absolute claudication distance (ACD) during the trial in patients treated with NCX 4016 or placebo. Data are shown as geometric means ± standard deviation and refer to the intima-media thickness (IMT) analysis. Journal of Vascular Surgery  , e5DOI: ( /j.jvs ) Copyright © 2012 Society for Vascular Surgery Terms and Conditions

4 Fig 3 Change from baseline in the mean intima-media thickness (IMT) of the right common carotid artery after 6 months of treatment with either NCX 4016 or placebo. Data represent means ± standard deviation. *P = vs baseline. Journal of Vascular Surgery  , e5DOI: ( /j.jvs ) Copyright © 2012 Society for Vascular Surgery Terms and Conditions

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