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More Is Less: IL-9 in the Resolution of Inflammation

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Presentation on theme: "More Is Less: IL-9 in the Resolution of Inflammation"— Presentation transcript:

1 More Is Less: IL-9 in the Resolution of Inflammation
Fotios Karagiannis, Christoph Wilhelm  Immunity  Volume 47, Issue 3, Pages (September 2017) DOI: /j.immuni Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 The Function of IL-9 in the Resolution of Joint Inflammation in RA Rauber et al. (2017) found that autocrine IL-9 expands the ILC2 pool and upregulates the expression of ICOS ligand (ICOSL) and GITR ligand (GITRL) on ILC2s. Increased expression of these ligands boosts the suppressive capacity of Treg cells to suppress Th17-mediated joint inflammation, resulting in the resolution of inflammation. Immunity  , DOI: ( /j.immuni ) Copyright © 2017 Elsevier Inc. Terms and Conditions


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