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Peter Kuckenberg, Caroline Kubaczka, Hubert Schorle 

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Presentation on theme: "Peter Kuckenberg, Caroline Kubaczka, Hubert Schorle "— Presentation transcript:

1 The role of transcription factor Tcfap2c/TFAP2C in trophectoderm development 
Peter Kuckenberg, Caroline Kubaczka, Hubert Schorle  Reproductive BioMedicine Online  Volume 25, Issue 1, Pages (July 2012) DOI: /j.rbmo Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions

2 Figure 1 Schematic of gene network orchestrating trophoblast development. Blue=genes implicated in specification of trophoblast fate; light blue=genes required for trophoblast maintenance; red=genes required for inner cell mass maintenance; grey=genes responsible for trophectoderm differentiation. (For interpretation of the references to colours in this figure legend, the reader is referred to the web version at this paper.) Reproductive BioMedicine Online  , 12-20DOI: ( /j.rbmo ) Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions

3 Figure 2 Expression of TFAP2 proteins in human placenta. Serial sections of a human placenta at 8 weeks of gestation processed with antibodies to detect TFAP2A (A) and TFAP2C (B). Red arrows=syncytiotrophoblast layer; green arrows=cytotrophoblast cells. EVT=extravillous trophoblast cells invading the decidua. Bars=100μm. (For interpretation of the references to colours in this figure legend, the reader is referred to the web version of this paper.) Reproductive BioMedicine Online  , 12-20DOI: ( /j.rbmo ) Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions


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