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A TRIM16-Galectin3 Complex Mediates Autophagy of Damaged Endomembranes

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Presentation on theme: "A TRIM16-Galectin3 Complex Mediates Autophagy of Damaged Endomembranes"— Presentation transcript:

1 A TRIM16-Galectin3 Complex Mediates Autophagy of Damaged Endomembranes
Milana Fraiberg, Zvulun Elazar  Developmental Cell  Volume 39, Issue 1, Pages 1-2 (October 2016) DOI: /j.devcel Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 The TRIM16-Galectin3 Complex Serves as a Platform for the Initiation of Autophagy-Mediated Damaged Endomembrane Response Endomembrane injury exposes β-galactoside glycoconjugates that recruit Galectin3, which in turn interacts with TRIM16. The resulting complex associates with the core autophagic machinery, including Beclin1, ULK1, and ATG16L1, to promote local formation of the autophagic membrane. Developmental Cell  , 1-2DOI: ( /j.devcel ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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