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Therapeutic effects of the levonorgestrel-releasing intrauterine system in the treatment of idiopathic menorrhagia  Bilian Xiao, M.D., Shang-Chun Wu,

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Presentation on theme: "Therapeutic effects of the levonorgestrel-releasing intrauterine system in the treatment of idiopathic menorrhagia  Bilian Xiao, M.D., Shang-Chun Wu,"— Presentation transcript:

1 Therapeutic effects of the levonorgestrel-releasing intrauterine system in the treatment of idiopathic menorrhagia  Bilian Xiao, M.D., Shang-Chun Wu, M.S., Jie Chong, Tao Zeng, L.i-Hui Han, M.S., Tapani Luukkainen, M.D., Ph.D.  Fertility and Sterility  Volume 79, Issue 4, Pages (April 2003) DOI: /S (02)

2 FIGURE 1 Trial profile. The total number of women at admission was 34. The total number of months of follow-up was 1,125. Two patients were lost to follow-up (one at 3 months and one at 19 months). Four women expelled the LNG-IUS (at day 2 and at month 1, 3, and 15). Two women underwent premature removal (at month 7 and 16). At the end of the study (36 months), there were 24 women. Two women participated less than 36 months but still had follow-up at 24 and 30 months, respectively. IUSs in four women were removed at the end of the study (at 36, 44, 48, and 52 months). Ten subjects were followed-up more than 48 months. Xiao. Treatment of menorrhagia with LNG-IUS.Fertil Steril 2003. Fertility and Sterility  , DOI: ( /S (02) )

3 FIGURE 2 Changes of MBL before and after LNG-IUS insertion. Changes of MBL of each individual are expressed in the linear graphs, with dots indicating the MBL value at pretreatment cycles (−2 months and −1 month) and at 6, 12, 24, and 36 months of follow-up. MBL decreased markedly at 6 months in all women. In one case (---), MBL was very high before treatment (259.6 and 150 mL) and decreased to 100 mL at 12 months; thus, it remained higher than the limit of menorrhagia, but the patient became amenorrheic after 24 months. Xiao. Treatment of menorrhagia with LNG-IUS.Fertil Steril 2003. Fertility and Sterility  , DOI: ( /S (02) )


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