1. Nodal/Activin Signaling: A Novel Target for Pancreatic Cancer Stem Cell Therapy 
Timothy R. Donahue, David W. Dawson 
Cell Stem Cell 
Volume 9, Issue 5, Pages (November 2011)
DOI: /j.stem
Copyright © 2011 Elsevier Inc. Terms and Conditions

2. Figure 1
Nodal/Activin Signaling Maintains PDAC Stem Cells in the Tumor Stromal Microenvironment
Inhibition of Alk receptor inhibitor by SB blocks autocrine and potential paracrine Nodal signaling, sensitizing CSCs to chemotherapy. Inhibition of the Hedgehog pathway with CUR disrupts the stroma and also may directly influence CSCs.
Cell Stem Cell 2011 9, DOI: ( /j.stem )
Copyright © 2011 Elsevier Inc. Terms and Conditions