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Volume 18, Issue 3, Pages 269-285 (March 2019)
Global, regional, and national burden of multiple sclerosis 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 Mitchell T Wallin, William J Culpepper, Emma Nichols, Zulfiqar A Bhutta, Tsegaye Tewelde Gebrehiwot, Simon I Hay, Ibrahim A Khalil, Kristopher J Krohn, Xiaofeng Liang, Mohsen Naghavi, Ali H Mokdad, Molly R Nixon, Robert C Reiner, Benn Sartorius, Mari Smith, Roman Topor-Madry, Andrea Werdecker, Theo Vos, Valery L. Feigin, Christopher J L Murray Mitchell T Wallin, William J Culpepper, Emma Nichols, Zulfiqar A Bhutta, Tsegaye Tewelde Gebrehiwot, Simon I Hay, Ibrahim A Khalil, Kristopher J Krohn, Xiaofeng Liang, Mohsen Naghavi, Ali H Mokdad, Molly R Nixon, Robert C Reiner, Benn Sartorius, Mari Smith, Roman Topor-Madry, Andrea Werdecker, Theo Vos, Valery L. Feigin, Christopher J L Murray The Lancet Neurology Volume 18, Issue 3, Pages (March 2019) DOI: /S (18) Copyright © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions
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Figure 1 Age-standardised multiple sclerosis prevalence per 100 000 population in 2016 for both sexes, by location ATG=Antigua and Barbuda. Isl=Islands. LCA=Saint Lucia. VCT=Saint Vincent and the Grenadines. TTO=Trinidad and Tobago. TLS=Timor-Leste. FSM=Federated States of Micornesia. The Lancet Neurology , DOI: ( /S (18) ) Copyright © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions
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Figure 2 Age-standardised prevalence of multiple sclerosis in 2016, by age and sex Shading shows 95% uncertainty intervals. The Lancet Neurology , DOI: ( /S (18) ) Copyright © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions
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Figure 3 YLDs and YLLs due to multiple sclerosis in 2016, by age
Shading shows 95% uncertainty intervals. YLDs=years lived with disability. YLLs=years of life lost. The Lancet Neurology , DOI: ( /S (18) ) Copyright © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions
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Figure 4 Age-standardised DALYs for multiple sclerosis by SDI, 1990–2016, and expected value-based SDI The black line represents the average expected relationship between SDI and DALYs for multiple sclerosis based on values from all countries over the 1990–2016 estimation period. DALYs= disability-adjusted life-years. SDI=Socio-demographic Index. The Lancet Neurology , DOI: ( /S (18) ) Copyright © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions
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