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Volume 24, Issue 20, Pages R988-R993 (October 2014)
Adipocytes Rana K. Gupta Current Biology Volume 24, Issue 20, Pages R988-R993 (October 2014) DOI: /j.cub Copyright © 2014 Elsevier Ltd Terms and Conditions
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Figure 1 Properties of adipose tissue in rodents and humans.
Current Biology , R988-R993DOI: ( /j.cub ) Copyright © 2014 Elsevier Ltd Terms and Conditions
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Figure 2 Manipulating adipose development to combat chronic disease.
(A) Increasing the number of fat cells, rather than the size of fat cells, in the face of positive energy balance may lead to healthier adipose tissue in the obese setting. (B) Likewise, directing excessive energy towards subcutaneous adipose, rather than visceral regions, may help improve metabolic health in the setting of obesity and lower the risk for cardiometabolic disease and cancer. (C) Direct reprogramming of white preadipocytes/adipocytes into energy-burning brown/beige adipocytes may be an effective treatment for weight loss or insulin resistance in the setting of obesity. Inhibiting the formation of thermogenic adipocytes or converting them to white adipocytes may help combat cancer cachexia. Current Biology , R988-R993DOI: ( /j.cub ) Copyright © 2014 Elsevier Ltd Terms and Conditions
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