1. Angew. Chem. Int. Ed., 2010, 49, Early View
Light-Driven Transport of a Molecular Walker in Either Direction along a Molecular Track
Michael J. Barrell, Araceli G. Campaa, Max von Delius,
Edzard M. Geertsema, and David A. Leigh*
School of Chemistry, University of Edinburgh
The King’s Buildings, West Mains Road, Edinburgh EH9 3JJ (UK)
Nat. Chem., 2010, 2,
J. Am. Chem. Soc., 2010, 132, ASAP

2. Linear Molecular Motor
<Nature System>
M. Schliwa and G. Woehlke, Nature, 2003, 422,
Bipedal Motor Proteins
Nature, 2007, 445,
Nature, 2003, 424, ; JACS, 2008, 130, ;
JACS, 2006, 128, ; Science, 2004, 306, ;
Angew. Chem. Int. Ed., 2007, 46, ; etc…..

3. A Molecular Walker-Track System
Acid: Lock
Base: Labile
Acid: Labile
Base: Lock
D. A. Leigh. et al., Nat. Chem., 2010, 2,

4. A Molecular Walker-Track System
S. Otto, Nat. Chem.,
2010, 2,
D. A. Leigh. et al.,
Nat. Chem., 2010, 2,

5. A Light-driven Walker-Track System

6. Synthesis of Molecular Walker-Track Conjugate

7. Directional Biased Walker Migration

8. 1H NMR Spectra of Each Isomer of 1
(500 MHz, CD2Cl2)

9. 1H NMR Spectra of Each Isomer of 1
(500 MHz, CD2Cl2)

10. Dynamic Behavior of Walker-Track System
acid
365 nm
500 nm
base

11. Dynamic Behavior of Walker-Track System
base
500 nm
365 nm
acid

12. Dynamic Behavior of Walker-Track System
base
acid
base
acid

13. By-products

14. Energy Ratchet Mechanism

15. Conclusions
A light-driven Walker-Track System