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Benjamin C. Sun, MD, Timothy A. Dickinson, CCP, Eric A

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Presentation on theme: "Benjamin C. Sun, MD, Timothy A. Dickinson, CCP, Eric A"— Presentation transcript:

1 The Unintended Consequences of Over-Reducing Cardiopulmonary Bypass Circuit Prime Volume 
Benjamin C. Sun, MD, Timothy A. Dickinson, CCP, Eric A. Tesdahl, PhD, Donald S. Likosky, PhD, Christopher Wells, MD, MBA, Samuel Weinstein, MD  The Annals of Thoracic Surgery  Volume 103, Issue 6, Pages (June 2017) DOI: /j.athoracsur Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Model-adjusted probability of packed red blood cells (RBC) transfusion of 1 or more units by prime volume ratio and first hematocrit in the operating room: 32 (solid line) or 40 (dotted line). (Hct = hematocrit; OR = operating room.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Model A: adjusted odds ratios for transfusion of 1 or more units packed red blood cells. (CPB = cardiopulmonary bypass; Est. = estimated; O.R. = operating room.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Model-adjusted probability of packed red blood cells (RBC) transfusion of 4 or more units by prime volume ratio and first hematocrit in the operating room: 32 (solid line) or 40 (dotted line). (Hct = hematocrit; OR = operating room.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Model B: adjusted odds ratios for transfusion of 4 or more units packed red blood cells. (CPB = cardiopulmonary bypass; Est. = estimated; O.R. = operating room.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

6 Fig 5 Distribution of last the hematocrit in the operating room (O.R.) for the 36,818 patients who did not receive a transfusion. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

7 Supplemental Figure 1 The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

8 Supplemental Figure 2 The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

9 Supplemental Figure 3 The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

10 Supplemental Figure 4 The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

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