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Bim Expression Is Reduced in Human Cutaneous Melanomas

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1 Bim Expression Is Reduced in Human Cutaneous Melanomas
Derek L. Dai, Yemin Wang, Min Liu, Magdalena Martinka, Gang Li  Journal of Investigative Dermatology  Volume 128, Issue 2, Pages (February 2008) DOI: /sj.jid Copyright © 2008 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Representative images of Bim immunohistochemical staining in human primary melanomas. (a) Negative Bim staining; (b) weak Bim staining; (c) moderate Bim staining; (d) strong Bim staining. Bar=10μm. Journal of Investigative Dermatology  , DOI: ( /sj.jid ) Copyright © 2008 The Society for Investigative Dermatology, Inc Terms and Conditions

3 Figure 2 Reduced Bim expression correlates with a worse 5-year patient survival. Reduced Bim staining correlates with a (a) poorer overall 5-year survival (P<0.001, log-rank test) and (b) disease-specific 5-year survival (P<0.001, log-rank test). Journal of Investigative Dermatology  , DOI: ( /sj.jid ) Copyright © 2008 The Society for Investigative Dermatology, Inc Terms and Conditions


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