1. Accuracy of Spleen Stiffness Measurement in Detection of Esophageal Varices in Patients With Chronic Liver Disease: Systematic Review and Meta-analysis 
Siddharth Singh, John E. Eaton, Mohammad H. Murad, Hironori Tanaka, Hiroko Iijima, Jayant A. Talwalkar 
Clinical Gastroenterology and Hepatology 
Volume 12, Issue 6, Pages e4 (June 2014)
DOI: /j.cgh
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2. Figure 1 Flow diagram summarizing study identification and selection.
Clinical Gastroenterology and Hepatology  , e4DOI: ( /j.cgh )
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3. Figure 2
(A) Forest plots and meta-analyses of studies evaluating the sensitivity of SSM compared with EGD for the detection of any EVs in patients with chronic liver disease. (B) Forest plots and meta-analyses of studies evaluating the specificity of SSM compared with EGD for the detection of any EVs in patients with chronic liver disease.
Clinical Gastroenterology and Hepatology  , e4DOI: ( /j.cgh )
Copyright © 2014 AGA Institute Terms and Conditions

4. Figure 3
(A) Forest plots and meta-analyses of studies evaluating the sensitivity of SSM compared with EGD for the detection of clinically significant EVs in patients with chronic liver disease. (B) Forest plots and meta-analyses of studies evaluating the specificity of SSM compared with EGD for the detection of clinically significant EVs in patients with chronic liver disease.
Clinical Gastroenterology and Hepatology  , e4DOI: ( /j.cgh )
Copyright © 2014 AGA Institute Terms and Conditions

5. Supplementary Figure 1
Summary ROC curve for all 12 studies examining SSM compared with EGD for the detection of any EVs. SE, standard error.
Clinical Gastroenterology and Hepatology  , e4DOI: ( /j.cgh )
Copyright © 2014 AGA Institute Terms and Conditions

6. Supplementary Figure 2
Fagan nomogram estimating the post-test probability of EV, depending on the pretest clinical suspicion and results of spleen elastography. (A) With a pretest probability of EV of 25% (low clinical suspicion, as observed in patients with compensated cirrhosis), the post-test probability of EV, given a negative SSM (red), is 6%, and given a positive SSM (blue), is 53%. (B) With a pretest probability of EV of 50% (as observed in patients with decompensated cirrhosis), the post-test probability of EV, given a negative SSM (red), is 16%, and given a positive SSM (blue), is 78%. (C) With a hypothetical pretest probability of EV of 75%, the posttest probability of EV, given a negative SSM (red), is 36% and given a positive SSM (blue), is 91%.
Clinical Gastroenterology and Hepatology  , e4DOI: ( /j.cgh )
Copyright © 2014 AGA Institute Terms and Conditions

7. Supplementary Figure 3
Summary ROC curve for 9 studies examining SSM compared with EGD for the detection of clinically significant EVs. SE, standard error.
Clinical Gastroenterology and Hepatology  , e4DOI: ( /j.cgh )
Copyright © 2014 AGA Institute Terms and Conditions