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Changes in the 24-h plasma cortisol rhythm in patients with cirrhosis

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Presentation on theme: "Changes in the 24-h plasma cortisol rhythm in patients with cirrhosis"— Presentation transcript:

1 Changes in the 24-h plasma cortisol rhythm in patients with cirrhosis
Sara Montagnese, Benita Middleton, Ali R. Mani, Debra J. Skene, Marsha Y. Morgan  Journal of Hepatology  Volume 54, Issue 3, Pages (March 2011) DOI: /j.jhep Copyright © 2010 European Association for the Study of the Liver Terms and Conditions

2 Fig. 1 Plasma free cortisol (PFC) 24-h concentration-time curves in healthy volunteers (grey squares) and patients with cirrhosis (black rhomboids). Healthy volunteers showed a morning PFC double peak (06.00 and – grey bar) and patients with cirrhosis showed a delayed PFC peak (10.00 and – black bar). Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2010 European Association for the Study of the Liver Terms and Conditions

3 Fig. 2 Plasma free cortisol (PFC) 24-h concentration-time curves in patients with Child’s A cirrhosis (black circles) and patients with Child’s B/C cirrhosis (grey triangles). Patients with Child’s B/C cirrhosis showed a more prominent delay in the timing of the cortisol peak compared to their counterparts with Child’s A cirrhosis, although statistical significance was not reached. Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2010 European Association for the Study of the Liver Terms and Conditions


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