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Wine-induced asthma: A placebo-controlled assessment of its pathogenesis  Hassan Vally, BSc (Hons), Amanda Carr, BAppSc, Jacque El-Saleh, RN, Philip Thompson,

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Presentation on theme: "Wine-induced asthma: A placebo-controlled assessment of its pathogenesis  Hassan Vally, BSc (Hons), Amanda Carr, BAppSc, Jacque El-Saleh, RN, Philip Thompson,"— Presentation transcript:

1 Wine-induced asthma: A placebo-controlled assessment of its pathogenesis 
Hassan Vally, BSc (Hons), Amanda Carr, BAppSc, Jacque El-Saleh, RN, Philip Thompson, FRACP  Journal of Allergy and Clinical Immunology  Volume 103, Issue 1, Pages (January 1999) DOI: /S (99) Copyright © 1999 Mosby, Inc. Terms and Conditions

2 Fig. 1 Change in FEV1 in response to red wine (filled boxes) and red wine placebo (open boxes) in subject 3. Baseline FEV1 is represented by the horizontal dashed line . Journal of Allergy and Clinical Immunology  , 41-46DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

3 Fig. 2 Scattergram shows the VAS scores recorded by subjects with asthma in response to wine challenges (n = 16). Bars indicate mean values. Journal of Allergy and Clinical Immunology  , 41-46DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

4 Fig. 3 Change in FEV1 in response to high-sulfite wine challenge in subjects who provided a food history suggestive of a sensitivity to sulfites: subject 1 (open circles), subject 3 (filled boxes), subject 6 (filled circles), subject 11 (open boxes), and the average change in FEV1 in response to low-sulfite challenge in these subjects, n = 4 (*). Baseline FEV1 represented by the horizontal dashed line. Journal of Allergy and Clinical Immunology  , 41-46DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

5 Fig. 4 Response of subject 15 to high-sulfite wine challenge (filled boxes) and to repeat low-sulfite wine challenges, challenge 1 (open boxes) and challenge 2 (open triangles) . Journal of Allergy and Clinical Immunology  , 41-46DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

6 Fig. 5 Responsiveness of 3 subjects to specific problem wines: subject 1 (filled triangles), subject 8 (open boxes), subject 15 (filled boxes), and the average change in FEV1 in response to control challenges, n = 3 (*). Baseline FEV1 represented by horizontal dashed line. Journal of Allergy and Clinical Immunology  , 41-46DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions


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