1. Optimizing Front-Line Endocrine Therapy in Metastatic Breast Cancer

2. Faculty

3. Introduction

4. Introduction (cont)

5. Treatment in the First-Line Setting

6. Clinical Case 1: Postmenopausal Woman

7. Clinical Case 1: First-Line Treatment

8. Clinical Case 1: Disease Progression

9. Case 1: How Would You Treat?

10. Case 1: Treatment Discussion

11. FALCON: Study Design

12. FALCON: Results

13. FALCON Subset Analysis: Fulvestrant in Patients With Nonvisceral Disease[a,b]

14. Implications for Patients

15. Case 1a: Alternate Scenario

16. Case 1a: Inclusion Criteria for Metastatic Breast Cancer Studies

17. Case 1a: Treatment Discussion

18. PALOMA-2 and MONALEESA-2: Results

19. PALOMA-2 and MONALEESA-2: Safety

20. Case 1b: Alternate Scenario

21. Case 1b: Alternate Scenario (cont)

22. Case 1b: Treatment Discussion

23. Case 1b: Treatment Discussion (cont)

24. Case 1b: Treatment Discussion (cont)

25. Treatment in the Second-Line Setting

26. Treatment in the Second-Line Setting

27. Treatment in the Second-Line Setting (cont)

28. Treatment in the Second-Line Setting (cont)

29. Conclusions

30. Abbreviations

31. Abbreviations (cont)