1. Is the Monocyte Chemotactic Protein-1 −2518 G Allele a Risk Factor for Severe Acute Pancreatitis? 
Georgios I. Papachristou, David A. Sass, Haritha Avula, Janette Lamb, Anna Lokshin, M. Michael Barmada, Adam Slivka, David C. Whitcomb 
Clinical Gastroenterology and Hepatology 
Volume 3, Issue 5, Pages (May 2005)
DOI: /S (05)
Copyright © 2005 American Gastroenterological Association Terms and Conditions

2. Figure 1
Frequencies of G allele presence or absence in controls, MAP, and SAP. □, Percent of patients with A/A genotypes (a); ■, percent of patients with A/G or G/G genotypes (g).
Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (05) )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

3. Figure 2
Serum MCP-1 levels of the 77 patients with acute pancreatitis. The boxes represent the median and 25th and 75th percentiles of the MCP-1 values and the bars encompass approximately 95% of all values. Values considered as possible outliers also are plotted.
Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (05) )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

4. Figure 3
Clinical severity as a function of pancreatic injury. Hypothetical effect of the MCP-1 −2518 G allele on shifting the injury/severity curve to the left. Note that with a moderate level of pancreatic injury, a, patients with the MCP-1 −2518 A/G or G/G genotype would develop SAP whereas patients with the MCP-1 A/A genotype would have only MAP. If the injury were extensive, b, then all patients would have a severe course, but patients with the A/G or G/G genotype might be at risk for death.
Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (05) )
Copyright © 2005 American Gastroenterological Association Terms and Conditions