1. Characterization and comparison of recombinant human and rat TRPV1 receptors: effects of exo- and endocannabinoids†  
P.M.W. Lam, J. McDonald, D.G. Lambert 
British Journal of Anaesthesia 
Volume 94, Issue 5, Pages (May 2005)
DOI: /bja/aei098
Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

2. Fig 1 Structures of capsaicin and anandamide.
British Journal of Anaesthesia  , DOI: ( /bja/aei098)
Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

3. Fig 2
Typical traces obtained from fluorimetric measurements in a capsaicin concentration–response curve: (a) hTRPV1, 22°C; (b) rTRPV1, 22°C; (c) hTRPV1, 37°C; (d) rTRPV1, 37°C. Arrows indicate the addition of capsaicin at 60 s. Data are from single representative experiments as shown in Table 1.
British Journal of Anaesthesia  , DOI: ( /bja/aei098)
Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

4. Fig 3
Concentration response curves for capsaicin (Cap) and AEA: (a) hTRPV1, 22°C; (b) rTRPV1, 22°C; (c) hTRPV1, 37°C; (d) rTRPV1, 37°C. Data are mean (sem) (n=3–7).
British Journal of Anaesthesia  , DOI: ( /bja/aei098)
Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

5. Fig 4
Capsazepine (Cpz) 30 μM produced a rightward shift in the concentration–response curve to capsaicin indicative of competitive antagonism. Data (mean [sem], n=3–4) are normalized to the maximum capsaicin response in each individual experiment. (a) hTRPV1, 22°C; (b) rTRPV1, 22°C; (c) hTRPV1, 37°C; (d) rTRPV1, 37°C.
British Journal of Anaesthesia  , DOI: ( /bja/aei098)
Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

6. Fig 5
Effect of ethanol and THC on [Ca2+]i at hTRPV1 at 37°C. Addition of (a) THC 100 μM and (b) ethanol 170 mM (indicated by the initial arrows) produced a capsazepine-sensitive increase in [Ca2+]i. Capsazepine (Cpz) or DMSO addition is shown by the later arrow (capsazepine 30 μM in DMSO to 0.3% v/v final). (c) Ethanol concentration response at hTRPV1 at 22°C (n=4) and 37°C (n=5). Data are mean (sem).
British Journal of Anaesthesia  , DOI: ( /bja/aei098)
Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

7. Fig 6
Effects of capsaicin (Cap), AEA and THC on [35S]GTPγS binding to CB1 receptors in rat cerebellar membranes. Data are mean (sem) (n=3) and are expressed as stimulation factor (ratio of agonist-stimulated specific binding to basal specific binding).
British Journal of Anaesthesia  , DOI: ( /bja/aei098)
Copyright © 2005 British Journal of Anaesthesia Terms and Conditions