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Inside the Chamber of Secrets of the Type III Secretion System

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1 Inside the Chamber of Secrets of the Type III Secretion System
Eric Cascales  Cell  Volume 168, Issue 6, Pages (March 2017) DOI: /j.cell Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 Architecture of the Salmonella Type III Secretion Injectisome
(A) Schematic representation of a Salmonella cell with assembled SPI-1 type III secretion systems. A magnification of the secretion apparatus is shown in (B). (B) Architecture of the Salmonella type III secretion system’s (T3SS’s) injectisome, as revealed by cryo-ET. The localizations of the different subunits (see color code on left) are indicated: OM, outer membrane; PG, peptidoglycan; IM, inner membrane; OR, outer ring; IR, inner ring; CP, cytoplasmic platform. For each protein, the unified T3SS Sct nomenclature is indicated, as well as the name of the orthologs in Yersinia (Ysc), Shigella (Spa/Mxi), Salmonella (Inv/Prg/Org), and the flagellum (Fli, Flh). The dash denotes absence of orthologs. Cell  , DOI: ( /j.cell ) Copyright © 2017 Elsevier Inc. Terms and Conditions

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