1. Pathophysiology Of Diabetes Mellitus
Pancreas
Pathophysiology Of
Diabetes
Mellitus
Failure to produce insulin
Elevated blood glucose levels
Destruction of alpha and beta cells
Increased osmolarity due to elevated glucose
Ketonuria
Production of excess glucagon
↑ Destruction of alpha & beta cells
↑ Ketones
Production of glucose from protein & fat stores
Kussmaul
Respirations
Glycosuria, polydipsia, polyphagia, polyuria
Acidosis
Wasting of lean body mass
Acetone
Breath
Weight Loss
Fatigue
Weight Loss
Chronic elevations in blood glucose
Impaired Immune Function
Accelerated
Atherosclerosis
Small Vessel Disease
Diabetic
Retinopathy
Diabetic
Neuropathy
Diabetic
Nephropathy