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Preventing Bacterial Suicide: A Novel Toxin-Antitoxin Strategy

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1 Preventing Bacterial Suicide: A Novel Toxin-Antitoxin Strategy
Monica Markovski, Sue Wickner  Molecular Cell  Volume 52, Issue 5, Pages (December 2013) DOI: /j.molcel Copyright © 2013 Elsevier Inc. Terms and Conditions

2 Figure 1 The SocAB System Is a New Class of Toxin-Antitoxin Modules
(A) Unlike canonical toxin-antitoxin systems, the SocA antitoxin (purple) acts as a proteolytic adaptor for the degradation of SocB toxin (red) by the protease ClpXP (gray). (B) The five types of toxin-antitoxin systems are classified based on the mechanism of action the antitoxin (purple) employs to inactivate toxin (red) activity. AT, antitoxin; T, toxin. Molecular Cell  , DOI: ( /j.molcel ) Copyright © 2013 Elsevier Inc. Terms and Conditions

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