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Non-invasive metabolic monitoring of patients under anaesthesia by continuous indirect calorimetry—an in vivo trial of a new method  C. Stuart-Andrews,

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Presentation on theme: "Non-invasive metabolic monitoring of patients under anaesthesia by continuous indirect calorimetry—an in vivo trial of a new method  C. Stuart-Andrews,"— Presentation transcript:

1 Non-invasive metabolic monitoring of patients under anaesthesia by continuous indirect calorimetry—an in vivo trial of a new method  C. Stuart-Andrews, P. Peyton, G. Robinson, D. Terry, B. O'Connor, C. Van der Herten, B. Lithgow  British Journal of Anaesthesia  Volume 98, Issue 1, Pages (January 2007) DOI: /bja/ael310 Copyright © 2007 British Journal of Anaesthesia Terms and Conditions

2 Fig 1 Schematic diagram of the anaesthetic circuit and measurement system setup. A standard anaesthetic semi closed circle absorber circuit, incorporating a soda lime canister was attached to an anaesthetic delivery system, consisting of an anaesthetic machine and ventilator. Continuous side-stream sampling of exhaust gas by the gas analyser was done, with intermittent fresh gas sampling for calibration of the system. A computer collected data from the transducer and gas analyser and calculated and recorded the gas exchange values. British Journal of Anaesthesia  , 45-52DOI: ( /bja/ael310) Copyright © 2007 British Journal of Anaesthesia Terms and Conditions

3 Fig 2 A Bland–Altman plot showing the difference between paired simultaneous measurements of V ˙ O 2 (calculated as V ˙ O 2 CIC − V ˙ O 2 Fick ). The mean bias and upper and lower limits of agreement are indicated. The crossed points indicate measurements made pre-bypass, while those without indicate post-bypass measurements. British Journal of Anaesthesia  , 45-52DOI: ( /bja/ael310) Copyright © 2007 British Journal of Anaesthesia Terms and Conditions

4 Fig 3 A continuous plot of measured V ˙ O 2 values at STPD plotted at 15 s intervals from a patient undergoing cardiopulmonary bypass graft surgery. The patient's ECG rhythm changed in a stepwise fashion from a normal sinus rhythm (SR) to rapid atrial fibrillation (AF), accompanied by a decrease in systemic arterial pressure of 15–20%. An increase of approximately 20% in V ˙ O 2 was measured until cardiopulmonary bypass was commenced and ventilation of the patient's lungs was stopped. A parallel increase in exhaust gas CO2 concentration occurred as well. British Journal of Anaesthesia  , 45-52DOI: ( /bja/ael310) Copyright © 2007 British Journal of Anaesthesia Terms and Conditions


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