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Histomorphometric analysis of intrapulmonary vessels in patients undergoing bidirectional Glenn shunt and total cavopulmonary connection  Ujjwal K. Chowdhury,

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Presentation on theme: "Histomorphometric analysis of intrapulmonary vessels in patients undergoing bidirectional Glenn shunt and total cavopulmonary connection  Ujjwal K. Chowdhury,"— Presentation transcript:

1 Histomorphometric analysis of intrapulmonary vessels in patients undergoing bidirectional Glenn shunt and total cavopulmonary connection  Ujjwal K. Chowdhury, MCh, Diplomate NB, Raghu M. Govindappa, MS, Prasenjit Das, MD (Pathol), Ruma Ray, MD (Pathol), FRC (Path), Mani Kalaivani, MSc (Biostatistics), Srikrishna M. Reddy, MCh  The Journal of Thoracic and Cardiovascular Surgery  Volume 140, Issue 6, Pages e14 (December 2010) DOI: /j.jtcvs Copyright © Terms and Conditions

2 The Journal of Thoracic and Cardiovascular Surgery 2010 140, 1251-1256
The Journal of Thoracic and Cardiovascular Surgery  , e14DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

3 Photomicrograph of lung biopsy specimen of patients undergoing univentricular repair showing 3 layers of a small intra-acinar pulmonary artery (A), morphometric measurements of circumferential area incorporating all 3 layers, diameter from one advential margin to the opposite advential margin (B), and endothelial versus medial thickness, where endothelial layer is markedly thickened with subendothelial edema (C). The Journal of Thoracic and Cardiovascular Surgery  , e14DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

4 A, Photomicrographs of the lung biopsy specimen of patients with tricuspid atresia showing normal 3 layers of a small intra-acinar pulmonary artery (hematoxylin and eosin stain, original magnification × 200). B, Photomicrographs of lung biopsy specimen of patients with functionally univentricular heart showing normal 3 layers of a small intra-acinar pulmonary artery (hematoxylin and eosin stain, original magnification ×200). The Journal of Thoracic and Cardiovascular Surgery  , e14DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

5 A, Photomicrograph of the lung biopsy specimen of a patient with tricuspid atresia showing mild medial hypertrophy of a small intra-acinar pulmonary artery (A, Masson's trichrome stain, original magnification ×200; B, hematoxylin and eosin stain, original magnification ×200). B, Photomicrographs of lung biopsy specimen of patients with functionally univentricular heart showing mild medial hypertrophy of a small intra-acinar pulmonary artery (A, B, hematoxylin and eosin stain, original magnification ×200; C, Masson's trichrome stain, original magnification ×200). The Journal of Thoracic and Cardiovascular Surgery  , e14DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

6 Photomicrograph of lung biopsy specimen of a patient with a functionally univentricular heart showing intimal thickening and subendothelial edema of a small intra-acinar pulmonary artery (hematoxylin and eosin stain, original magnification ×200). The Journal of Thoracic and Cardiovascular Surgery  , e14DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

7 Photomicrographs of lung biopsy specimen of patients with tricuspid atresia showing fresh intraluminal fibrin thrombus (A) and organizing intraluminal thrombus (B) of a small intra-acinar pulmonary artery (hematoxylin and eosin stain, original magnification ×200). The Journal of Thoracic and Cardiovascular Surgery  , e14DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

8 Photomicrographs of lung biopsy specimen of patients with tricuspid atresia showing alveolar hemorrhage of a small intra-acinar pulmonary artery (hematoxylin and eosin stain, original magnification ×200). The Journal of Thoracic and Cardiovascular Surgery  , e14DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

9 Photomicrographs of lung biopsy specimen of patients with tricuspid atresia showing muscularization of distal small intra-acinar pulmonary arteries (hematoxylin and eosin stain, original magnification ×200). The Journal of Thoracic and Cardiovascular Surgery  , e14DOI: ( /j.jtcvs ) Copyright © Terms and Conditions


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