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Elizabeth Mileti, Philip Rosenthal, Marion G. Peters 

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Presentation on theme: "Elizabeth Mileti, Philip Rosenthal, Marion G. Peters "— Presentation transcript:

1 Validation and Modification of Simplified Diagnostic Criteria for Autoimmune Hepatitis in Children 
Elizabeth Mileti, Philip Rosenthal, Marion G. Peters  Clinical Gastroenterology and Hepatology  Volume 10, Issue 4, Pages e2 (April 2012) DOI: /j.cgh Copyright © 2012 AGA Institute Terms and Conditions

2 Figure 1 Flow diagram of the initial 238 patients evaluated for inclusion in this study. Seventy-seven patients (37 AIH, 40 non-AIH) had complete laboratory, histologic, demographic, and clinical data available to calculate the 1999 AIH score. Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2012 AGA Institute Terms and Conditions

3 Supplementary Figure 1 Comparison of the ROC curves for the 2008 (closed diamonds) with the gold standard of the 1999 revised original scoring system (open circles) for the diagnosis of AIH. The AUROC for the 2008 criteria was 0.98. Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2012 AGA Institute Terms and Conditions

4 Supplementary Figure 2 Compares the ROC curves for the modified 2008 criteria, using either IgG or serum globulin, for the diagnosis of AIH (closed diamonds) with the gold standard of the 1999 revised original scoring system (open circles) for diagnosis of AIH. The AUROC for the modified 2008 criteria was 0.99. Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2012 AGA Institute Terms and Conditions


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