1. Aromatase inhibitor regulates let-7 expression and let-7f–induced cell migration in endometrial cells from women with endometriosis 
SiHyun Cho, M.D., Levent Mutlu, M.D., Yuping Zhou, B.S., Hugh S. Taylor, M.D. 
Fertility and Sterility 
Volume 106, Issue 3, Pages (September 2016)
DOI: /j.fertnstert
Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
Expression of let-7 microRNA family after treatment with letrozole for 48 hours. The concentration of letrozole is shown on the x axis in μmol/L. Data are shown as mean ± SEM. C = control. *P<.05; **P<.01. (A) Ishikawa cell lines (n = 3). (B) Endometrial stromal cells from subjects with endometriosis (n = 6).
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

3. Figure 2
Aromatase mRNA expression and Western blot analysis after treatment with the let-7f mimic and has-mir-negative control (Ctl) for 48 hours. Data are shown as mean ± SEM. *P<.05; **P<.01. (A) Ishikawa cell lines (n = 4). (B) Endometrial stromal cells from subjects with endometriosis (n = 4). (C) Western blot analysis of aromatase expression after treatment with let-7f mimic or has-mir-negative control for 48 hours.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

4. Figure 3
Effects on let-7f (mimic vs. has-mir-negative control [Ctl]) on cell migration in Ishikawa cell lines and endometrial stromal cells from patients with endometriosis with the use of Millicell cell culture insert system (top) and representative fields of migration cells on the membrane; magnification ×200 (bottom). Data are shown as mean ± SEM. *P<.05; **P<.01. (A) Ishikawa cell lines (n = 5). (B) Endometrial stromal cells from subjects with endometriosis (n = 5).
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

5. Figure 4
Let-7f expression after treatment with letrozole (LZ) and E2 (E) for 48 hours. Data are shown as mean ± SEM. (A) Ishikawa cell lines (n = 3). (B) Endometrial stromal cells from subjects with endometriosis (n = 3).
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions