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Published byWalter Kennedy Modified over 5 years ago
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Long-term results 8 years after autologous osteochondral transplantation: 7 T gagCEST and sodium magnetic resonance imaging with morphological and clinical correlation I. Krusche-Mandl, B. Schmitt, L. Zak, S. Apprich, S. Aldrian, V. Juras, K.M. Friedrich, S. Marlovits, M. Weber, S. Trattnig Osteoarthritis and Cartilage Volume 20, Issue 5, Pages (May 2012) DOI: /j.joca Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions
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Fig. 1 It shows patient two, 9.4 years after ACT at the MFC.
(A): Morphologic proton-density (PDw) FSE image. (B): Graphical overlay with T2 map. Colorbar represents relaxation times in [ms] → higher values = more water, disturbed collagen architecture. (C): Graphical overlay with gagCEST image. Colorbar represents gagCEST asymmetries in [%] → lower values, less PG content. (D): Graphical overlay with sodium image. Colorbar represents the sodium SNR values → lower values, less PG content. Osteoarthritis and Cartilage , DOI: ( /j.joca ) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions
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Fig. 2 T2 relaxation times measured in repair and native cartilage of patients. All patients exhibited higher T2 values in the repair tissue, which is a sign of increased relative water content as well as an impairment of the collagen matrix structure. Osteoarthritis and Cartilage , DOI: ( /j.joca ) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions
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Fig. 3 gagCEST asymmetry values measured in repair tissue and native tissue of patients. Native tissue exhibited higher values in all patients indicating increased cartilage GAG content compared to repair tissue. Osteoarthritis and Cartilage , DOI: ( /j.joca ) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions
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Fig. 4 Sodium SNR values measured in repair tissue and native tissue of patients. Similarly to gagCEST, native tissue exhibited higher values in all patients also indicating higher GAG content compared to repair tissue. Osteoarthritis and Cartilage , DOI: ( /j.joca ) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions
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Fig. 5 It shows patient five, 8 years after OCT at the MFC.
(A): Morphologic proton-density (PDw) FSE image. (B): Graphical overlay with T2 map. Colorbar represents relaxation times in [ms] → higher values = more water, disturbed collagen architecture. (C): Graphical overlay with gagCEST image. Colorbar represents gagCEST asymmetries in [%] → lower values, less PG content. (D): Graphical overlay with sodium image. Colorbar represents the sodium SNR values → lower values, less PG content. Osteoarthritis and Cartilage , DOI: ( /j.joca ) Copyright © 2012 Osteoarthritis Research Society International Terms and Conditions
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