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Epithelial cells as regulators of airway inflammation

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1 Epithelial cells as regulators of airway inflammation
Albert J. Polito, MDa, David Proud, PhDb  Journal of Allergy and Clinical Immunology  Volume 102, Issue 5, Pages (November 1998) DOI: /S (98) Copyright © 1998 Mosby, Inc. Terms and Conditions

2 Fig. 1 The epithelium produces cytokines that can recruit and activate inflammatory cells. The epithelium responds to a range of stimuli by producing chemoattractant cytokines, such as IL-8, eotaxin, and RANTES, that can recruit inflammatory cells to the airways. The production of colony-stimulating factors, such as GM-CSF, and of pleiotropic cytokines, such as IL-6, can further modulate the activation state of these cells—see text for details (© 1997 Jacqueline Schaffer). Journal of Allergy and Clinical Immunology  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions


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