1. Synthesis of (+)-Saxitoxin Fleming, J. J. ; Du Bois, J. Am. Chem. Soc
Songnan Zhang
04/02/2013
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2. Justin Du Bois B.S. 1992, University of California at Berkeley
Ph.D. 1997, California Institute of Technology
NIH Postdoctoral Fellow, Massachusetts Institute of Technology
Tetrahedron Young Investigator Award, 2008
John A. and Cynthia Fry Gunn University Fellows
in Undergraduate Education, 2011
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3. Publish:
1) “Modular Synthesis of the Pentacylic Core of Batrachotoxin and Select Batrachotoxin Analogue Designs,” A.S. Devlin, J. Du Bois, Chem. Sci., 4, (2013)  2) “A Designed Inhibitor of a CLC Antiporter Blocks Function Through a Unique Binding Mode,” A.E. Howery, S. Elvington, S.J. Abraham, K.-H. Choi, S. Philips, C.M. Ryan, R.L. Sanford, S. Simpson-Dworschak, J. Almqvist, K. Tran, T.A. Chew, U. Zachariae, O.S. Andersen, J. Whitelegge, K. Matulef, J. Du Bois, M. Maduke, Chem. Biol., 19, (2013)  3) “Capturing Fleeting Intermediates in a Catalytic C–H Amination Reaction Cycle,” R.H. Perry, T.J. Cahill III, J.L. Roizen, J. Du Bois, R. Zare, Proc. Natl. Acad. Sci. USA, 109, (2012)  4) “Marked Difference in Saxitoxin and Tetrodotoxin Affinities for the Human Nociceptive Voltage-gated Sodium Channel (NaV1.7),”  J.R. Walker, P. Novick, W.A. Parsons, M. McGregor, J. Zablocki, V.S. Pande, J. Du Bois, Proc. Natl. Acad. Sci. USA, 109, (2012)  5) “Fluorescent Saxitoxins for Live Cell Imaging of Voltage-gated Sodium Ion Channels Beyond the Optical Diffractin Limit,” A.E. Ondrus, H.-l.D. Lee, S. Iwanaga, W.H. Parsons, B.M. Andresen, W.E. Moerner, J. Du Bois, Chem. Biol., 19, (2012)  6) “Metal-Catalyzed Nitrogen-Atom Transfer Methods for the Oxidation of Aliphatic C–H Bonds,” M.E. Harvey, J.L. Roizen, Acc. Chem. Res., 45, (2012)  7) “Catalytic C–H Oxidation by a Triazamacrocyclic Ruthenium Complex,” E. McNeill, J. Du Bois, Chem. Sci., 3, (2012)  8) “A Diruthenium Catalyst for Selective, Intramolecular Allylic C–H Amination:  Reaction Development and Mechanistic Insight Gained Through Experiment and Theory,” M.E. Harvey, D.G. Musaev, J. Du Bois, J. Am. Chem. Soc., 133, (2011)
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4. Retrosynthesis
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9. QUESTIONS?
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