1. Near-tetraploidy is associated with Richter transformation in chronic lymphocytic leukemia patients receiving ibrutinib
by Cecelia R. Miller, Amy S. Ruppert, Nyla A. Heerema, Kami J. Maddocks, Jadwiga Labanowska, Heather Breidenbach, Gerard Lozanski, Weiqiang Zhao, Amber L. Gordon, Jeffrey A. Jones, Joseph M. Flynn, Samantha M. Jaglowski, Leslie A. Andritsos, Kristie A. Blum, Farrukh T. Awan, Kerry A. Rogers, Michael R. Grever, Amy J. Johnson, Lynne V. Abruzzo, Erin K. Hertlein, James S. Blachly, Jennifer A. Woyach, and John C. Byrd
BloodAdv
Volume 1(19):
August 22, 2017
© 2017 by The American Society of Hematology

2. Cecelia R. Miller et al. Blood Adv 2017;1:1584-1588
© 2017 by The American Society of Hematology

3. Near-tetraploidy is associated with Richter transformation on ibrutinib.
Near-tetraploidy is associated with Richter transformation on ibrutinib. (A) Cumulative incidence curves for transformation on ibrutinib with and without near-tetraploidy. (B) Cumulative incidence curves for transformation by near-tetraploidy and complex karyotype status. (C) Kaplan-Meier curves of OS for patients with or without near-tetraploidy. (D) Kaplan-Meier curves of OS by near-tetraploidy and complex karyotype status.
Cecelia R. Miller et al. Blood Adv 2017;1:
© 2017 by The American Society of Hematology