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Efficacy of high loading doses of liposomal amphotericin B in the treatment of experimental invasive pulmonary aspergillosis  J. Gavaldá, T. Martín, P.

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Presentation on theme: "Efficacy of high loading doses of liposomal amphotericin B in the treatment of experimental invasive pulmonary aspergillosis  J. Gavaldá, T. Martín, P."— Presentation transcript:

1 Efficacy of high loading doses of liposomal amphotericin B in the treatment of experimental invasive pulmonary aspergillosis  J. Gavaldá, T. Martín, P. López, X. Gomis, J.L. Ramírez, D. Rodríguez, Ó. Len, Y. Puigfel, I. Ruiz, A. Pahissa  Clinical Microbiology and Infection  Volume 11, Issue 12, Pages (December 2005) DOI: /j x Copyright © 2005 European Society of Clinical Infectious Diseases Terms and Conditions

2 Fig. 1 Effect of amphotericin B deoxycholate (d-AmB) vs. different regimens of liposomal amphotericin B (L-AmB) or control on the cumulative survival of steroid-immunosuppressed rats with invasive pulmonary aspergillosis. Filled squares, control; filled triangles, d-AmB 1 mg/kg/day; filled diamonds, L-AmB 5 mg/kg/day; open squares, L-AmB 10 mg/kg/day for 3 days; open circles, L-AmB 10 mg/kg/day for 3 days, followed by L-AmB 3 mg/kg/day; open triangles, L-AmB 10 mg/kg/day for 4 days, followed by L-AmB 3 mg/kg/day. Clinical Microbiology and Infection  , DOI: ( /j x) Copyright © 2005 European Society of Clinical Infectious Diseases Terms and Conditions


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