Presentation is loading. Please wait.

Presentation is loading. Please wait.

Ciliary and Nuclear Transport: Different Places, Similar Routes?

Published byGervais Allen Modified over 5 years ago

Similar presentations

Presentation on theme: "Ciliary and Nuclear Transport: Different Places, Similar Routes?"— Presentation transcript:

1 Ciliary and Nuclear Transport: Different Places, Similar Routes?
Samson O. Obado, Michael P. Rout  Developmental Cell  Volume 22, Issue 4, Pages (April 2012) DOI: /j.devcel Copyright © 2012 Elsevier Inc. Terms and Conditions

2 Figure 1 Structural and Transport Features of the Nuclear and Ciliary Pore Complexes Highlights of the similarities between the nuclear pore complex (A) and the ciliary barrier (B) showing the hypothetical route of a cargo protein through each type of barrier. (Position of each shown in inset diagram of ciliated eukaryotic cell.) FG Nups (containing Phenylalanine-Glycine repeats) provide docking sites for transport factors called karyopherins, which bind cargo containing nuclear or ciliary localization signals (NLSs and CLSs, respectively) and facilitate nuclear and ciliary transport. So-called transition zone proteins in cilia connect the plasma membrane and the region between the microtubules and the basal body. The ciliary pore complex is thought to be located in this zone. Figure 1A is adapted from Wente and Rout (2010). Developmental Cell  , DOI: ( /j.devcel ) Copyright © 2012 Elsevier Inc. Terms and Conditions

Download ppt "Ciliary and Nuclear Transport: Different Places, Similar Routes?"

Similar presentations

The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control Lei Zhang, Fangfang Ren, Qing Zhang, Yongbin Chen,

The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control Lei Zhang, Fangfang Ren, Qing Zhang, Yongbin Chen,
Mitotic Spindle Orientation in Asymmetric and Symmetric Cell Divisions during Animal Development Xavier Morin, Yohanns Bellaïche Developmental Cell Volume.

Mitotic Spindle Orientation in Asymmetric and Symmetric Cell Divisions during Animal Development Xavier Morin, Yohanns Bellaïche Developmental Cell Volume.
Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages 226-240 (August 2014) DOI: 10.1016/j.cmet.2014.07.001.

Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet
Nucleation and Transport Organize Microtubules in Metaphase Spindles Jan Brugués, Valeria Nuzzo, Eric Mazur, Daniel J. Needleman Cell Volume 149, Issue.

Nucleation and Transport Organize Microtubules in Metaphase Spindles Jan Brugués, Valeria Nuzzo, Eric Mazur, Daniel J. Needleman Cell Volume 149, Issue.
Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages 38-52 (April 2008) DOI: 10.1016/j.cell.2008.03.011.

Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell
Extracellular Matrix Protein Anosmin Promotes Neural Crest Formation and Regulates FGF, BMP, and WNT Activities Yukinori Endo, Hiroko Ishiwata-Endo, Kenneth.

Extracellular Matrix Protein Anosmin Promotes Neural Crest Formation and Regulates FGF, BMP, and WNT Activities Yukinori Endo, Hiroko Ishiwata-Endo, Kenneth.
Transcription Factor Binding to a DNA Zip Code Controls Interchromosomal Clustering at the Nuclear Periphery Donna Garvey Brickner, Sara Ahmed, Lauren.

Transcription Factor Binding to a DNA Zip Code Controls Interchromosomal Clustering at the Nuclear Periphery Donna Garvey Brickner, Sara Ahmed, Lauren.
Dynein Anchors Its mRNA Cargo after Apical Transport in the Drosophila Blastoderm Embryo Renald Delanoue, Ilan Davis Cell Volume 122, Issue 1, Pages 97-106.

Dynein Anchors Its mRNA Cargo after Apical Transport in the Drosophila Blastoderm Embryo Renald Delanoue, Ilan Davis Cell Volume 122, Issue 1, Pages
ER-to-Plasma Membrane Tethering Proteins Regulate Cell Signaling and ER Morphology Andrew G. Manford, Christopher J. Stefan, Helen L. Yuan, Jason A. MacGurn,

ER-to-Plasma Membrane Tethering Proteins Regulate Cell Signaling and ER Morphology Andrew G. Manford, Christopher J. Stefan, Helen L. Yuan, Jason A. MacGurn,
Neuronal Cell Types and Connectivity: Lessons from the Retina H. Sebastian Seung, Uygar Sümbül Neuron Volume 83, Issue 6, Pages 1262-1272 (September 2014)

Neuronal Cell Types and Connectivity: Lessons from the Retina H. Sebastian Seung, Uygar Sümbül Neuron Volume 83, Issue 6, Pages (September 2014)
LDL Cholesterol Recycles to the Plasma Membrane via a Rab8a-Myosin5b-Actin- Dependent Membrane Transport Route Kristiina Kanerva, Riikka-Liisa Uronen,

LDL Cholesterol Recycles to the Plasma Membrane via a Rab8a-Myosin5b-Actin- Dependent Membrane Transport Route Kristiina Kanerva, Riikka-Liisa Uronen,
Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages 255-266 (March 2014) DOI: 10.1016/j.cell.2014.03.012.

Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell
Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages 248-252 (April 2010) DOI: 10.1016/j.cmet.2010.03.008 Copyright © 2010.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.
Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila Gerasimos P. Sykiotis, Dirk Bohmann Developmental Cell Volume 14,

Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila Gerasimos P. Sykiotis, Dirk Bohmann Developmental Cell Volume 14,
The Metabolic Basis of Pulmonary Arterial Hypertension Gopinath Sutendra, Evangelos D. Michelakis Cell Metabolism Volume 19, Issue 4, Pages 558-573 (April.

The Metabolic Basis of Pulmonary Arterial Hypertension Gopinath Sutendra, Evangelos D. Michelakis Cell Metabolism Volume 19, Issue 4, Pages (April.
Competition between Blown Fuse and WASP for WIP Binding Regulates the Dynamics of WASP-Dependent Actin Polymerization In Vivo Peng Jin, Rui Duan, Fengbao.

Competition between Blown Fuse and WASP for WIP Binding Regulates the Dynamics of WASP-Dependent Actin Polymerization In Vivo Peng Jin, Rui Duan, Fengbao.
WHAMM Is an Arp2/3 Complex Activator That Binds Microtubules and Functions in ER to Golgi Transport Kenneth G. Campellone, Neil J. Webb, Elizabeth A. Znameroski,

WHAMM Is an Arp2/3 Complex Activator That Binds Microtubules and Functions in ER to Golgi Transport Kenneth G. Campellone, Neil J. Webb, Elizabeth A. Znameroski,
CDK Inhibitors: Cell Cycle Regulators and Beyond Arnaud Besson, Steven F. Dowdy, James M. Roberts Developmental Cell Volume 14, Issue 2, Pages 159-169.

CDK Inhibitors: Cell Cycle Regulators and Beyond Arnaud Besson, Steven F. Dowdy, James M. Roberts Developmental Cell Volume 14, Issue 2, Pages
LC3 Binding to the Scaffolding Protein JIP1 Regulates Processive Dynein-Driven Transport of Autophagosomes Meng-meng Fu, Jeffrey J. Nirschl, Erika L.F.

LC3 Binding to the Scaffolding Protein JIP1 Regulates Processive Dynein-Driven Transport of Autophagosomes Meng-meng Fu, Jeffrey J. Nirschl, Erika L.F.
Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages 305-320 (March 2005) DOI: 10.1016/j.devcel.2005.02.007.

Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel

Similar presentations

Ads by Google