1. Modified Hodge and EDTA-disk synergy tests to screen metallo-β-lactamase-producing strains of Pseudomonas and Acinetobactet species 
K. Lee, Y. Chong, H.B. Shin, Y.A. Kim, D. Yong, J.H. Yum 
Clinical Microbiology and Infection 
Volume 7, Issue 2, Pages (February 2001)
DOI: /j x
Copyright © 2001 European Society of Clinical Infectious Diseases Terms and Conditions

2. Figure 1
Modified Hodge test. A Mueller–Hinton agar plate was inoculated with E coli ATCC An imipenem disk was put in place and imipenem-resistant test isolates were streaked from the edge of the disk to the periphery of the plate and incubated overnight. (A) and (C) are imipenem-hydrolyzing strains which distorted the inhibition zone. (B) and (D) are imipenemnon-hydrolyzing strains with no effect on the zone.
Clinical Microbiology and Infection 2001 7, 88-91DOI: ( /j x)
Copyright © 2001 European Society of Clinical Infectious Diseases Terms and Conditions

3. Figure 2
EDTA-disk synergy test. A Mueller–Hinton agar plate was inoculated with an imipenem-resistant test isolate, and a 10-μg imipenem disk (left) and a 5 mM EDTA disk (right) were put in place and incubated overnight. (A) A synergistic inhibition zone is shown between an imipenem disk (left) and an EDTA disk (right) by a VIM-2 metallo-β-lactamase-producing strain. (B) Only a partially inhibited zone around an EDTA disk is shown by a metallo-β-lactamase-non-producing strain. (C) A metallo-β-lactamase-producing strain showing a small enhanced inhibition zone when the disks were placed 15 mm apart.
Clinical Microbiology and Infection 2001 7, 88-91DOI: ( /j x)
Copyright © 2001 European Society of Clinical Infectious Diseases Terms and Conditions