Presentation is loading. Please wait.

Presentation is loading. Please wait.

Matthew C. Henn, MD, Christopher P

Similar presentations


Presentation on theme: "Matthew C. Henn, MD, Christopher P"— Presentation transcript:

1 Dilated Cardiomyopathy: Normalized Multiparametric Myocardial Strain Predicts Contractile Recovery 
Matthew C. Henn, MD, Christopher P. Lawrance, MD, Julia Kar, PhD, Brian P. Cupps, PhD, Kevin Kulshrestha, Danielle Koerner, Kathleen Wallace, MSW, Susan Joseph, MD, Greg Ewald, MD, Michael K. Pasque, MD  The Annals of Thoracic Surgery  Volume 100, Issue 4, Pages (October 2015) DOI: /j.athoracsur Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Finite element model of the left ventricle with a grid of 15,300 left ventricular points divided into 18 subregions. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 The composite display of “normalized” microregional contractile function by intuitive Z-score color contour mapping (<1 standard deviation, blue; 1–2, yellow; >2, red) over patient-specific three-dimensional left ventricular geometry for all 24 DCM patients with dilated cardiomyopathy. (A = anterior; AL = anterolateral; AS = anteroseptal; P = posterior; PL = posterolateral; PS = posteroseptal.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Average multiparametric Z-scores over the six left ventricular regions from all 24 dilated cardiomyopathy patients. Data are represented as mean ± standard deviations. By analysis of variance, multiparametric Z-scores were found to vary significantly by region (p < 0.001), confirming regional heterogeneity. (A = anterior; AL = anterolateral; AS = anteroseptal; P = posterior; PL = posterolateral; PS = posteroseptal.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Average multiparametric Z-scores by left ventricular subregion. Data are represented as mean ± standard deviation. Basilar-septal sentinel region Z-scores were significantly higher (worse) when compared with the lateral wall or all other left ventricular regions. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

6 Fig 5 Average basilar-septal sentinel region multiparametric Z-scores of all 24 dilated cardiomyopathy patients grouped by recovery. Data are represented as mean ± standard deviations. The group with complete recovery had significantly lower (better) Z-scores when compared with the progressive failure group. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

7 Fig 6 Basilar-septal wall scatter plot of multiparametric Z-scores in all 24 dilated cardiomyopathy patients. (blue = complete recovery; red = progressive failure; yellow = partial recovery.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

8 Fig 7 Lateral wall scatter plot of multiparametric Z-scores in all 24 dilated cardiomyopathy patients. (blue = complete recovery; red = progressive failure; yellow = partial recovery.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions


Download ppt "Matthew C. Henn, MD, Christopher P"

Similar presentations


Ads by Google