1. Context Processing and the Neurobiology of Post-Traumatic Stress Disorder 
Israel Liberzon, James L. Abelson 
Neuron 
Volume 92, Issue 1, Pages (October 2016)
DOI: /j.neuron
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2. Figure 1
Neural Circuits within the Basolateral Complex of the Amygdala
Altered functioning within basolateral complex (BLC) circuits has been implicated in the Abnormal Fear Learning model of PTSD (see text). Interrupted lines represent distal inputs to and outputs from BLC.
Neuron  , 14-30DOI: ( /j.neuron )
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3. Figure 2 Brain Regions of the Salience Network
Abnormal function within Salience Network regions is implicated in the Exaggerated Threat Detection model of PTSD (see text).
Neuron  , 14-30DOI: ( /j.neuron )
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4. Figure 3
Brain Regions Involved in Executive Function and Emotional Regulation
Abnormal function in these regions has been implicated in the Diminished Executive Function and Emotional Regulation model of PTSD (see text).
Neuron  , 14-30DOI: ( /j.neuron )
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5. Figure 4 Brain Circuits Involved in Contextual Processing Functions
Abnormal function within these circuits is implicated in the Deficient Contextual Processing model of PTSD (see text). Information flow in this circuit includes Locus Coeruleus (LC) adrenergic neurons (shown in schematic but not visible in depicted brain slices).
Neuron  , 14-30DOI: ( /j.neuron )
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6. Figure 5
Contextual Processing Abnormalities in the Single Prolonged Stress Animal Model of PTSD and in PTSD Patients
(A) Schematic depiction of the SPS paradigm, which involves multiple stressors delivered sequentially in 1 day and then a 7 day “rest” period, followed by fear conditioning, extinction, and renewal testing.
(B) Data using this paradigm show abnormal fear renewal in SPS animals (seen on the right, in line graph and summary bar graph).
(C) Schematic depiction (including screen shots) of the paradigm used to examine fear conditioning, extinction, extinction recall and fear renewal in fMRI experiments with humans.
(D and E) Data using this paradigm with PTSD patients and combat control (CC) subjects show abnormal extinction recall (D) and abnormal fear renewal (E) in PTSD (skin conductance data shown on right in both panels). Differences in fMRI activations in PTSD compared to controls, in response to previously conditioned and then extinguished stimuli (CS+E), are shown on the left in both panels.
Neuron  , 14-30DOI: ( /j.neuron )
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