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Plasma and Peritoneal Dialysate Levels During Daptomycin Therapy for Peritonitis
Dmytro Khadzhynov, MD, Christian Joukhadar, MD, Harm Peters, MD American Journal of Kidney Diseases Volume 53, Issue 5, Pages (May 2009) DOI: /j.ajkd Copyright © 2009 National Kidney Foundation, Inc. Terms and Conditions
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Figure 1 (A) Peritoneal dialysis fluid and (B) blood trough concentrations of daptomycin in a patient with Gram-positive peritoneal dialysis–associated peritonitis. Daptomycin was given intravenously at a dose of 5 mg/kg body weight every 48 hours (open arrows). Peritoneal dialysis fluid was collected at the end of 3 daytime 4-hour periods (2 L Physioneal® 2.27% each) and 1 overnight 12-hour dwell time (2 L Extraneal® 7.5% per day). Daptomycin concentrations were measured by using high-performance liquid chromatography.6 The patient's hospital discharge is indicated. American Journal of Kidney Diseases , DOI: ( /j.ajkd ) Copyright © 2009 National Kidney Foundation, Inc. Terms and Conditions
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