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Amphiregulin Modifies the Minnesota Acute Graft-Versus-Host Disease Risk Score: Results from BMT CTN Acute Gvhd Therapy Trials  Shernan G. Holtan, Todd.

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Presentation on theme: "Amphiregulin Modifies the Minnesota Acute Graft-Versus-Host Disease Risk Score: Results from BMT CTN Acute Gvhd Therapy Trials  Shernan G. Holtan, Todd."— Presentation transcript:

1 Amphiregulin Modifies the Minnesota Acute Graft-Versus-Host Disease Risk Score: Results from BMT CTN Acute Gvhd Therapy Trials  Shernan G. Holtan, Todd E. Defor, Alan Howard, Joseph A. Pidala, John E. Levine, Juan Maggie Wu, Nandita Khera, Stephanie J. Lee, Javier Bolaños-Meade, Vincent T. Ho, Amin M. Alousi, Yoshihiro Inamoto, George L. Chen, Mukta Arora, Jeanne Palmer, Mary E. Flowers, Corey Cutler, Anne S. Renteria, Alexander Lukez, Sally Arai, Aleksandr Lazaryan, William J. Hogan, Laura F. Newell, Madan Jagasia, William A. Wood, M. Christa Krupski, Gregory A. Yanik, Udomsak Bunworasate, Elizabeth O. Hexner, Francis Ayuk, Ernst Holler, Sebastian Mayer, Iskra Pusic, Hien K. Duong, Yvonne A. Efebera, James Ferrara, Bruce R. Blazar, Angela Mortari, Daniel J. Weisdorf, Margaret L. MacMillan  Biology of Blood and Marrow Transplantation  Volume 24, Issue 3, Pages S177-S178 (March 2018) DOI: /j.bbmt Copyright © Terms and Conditions

2 Figure 1 Proportion of patients (+/- 95% confidence interval) experiencing clinical endpoints of day 28 complete response/partial response (CR/PR), overall survival (OS), and 2-year non-relapse mortality (NRM) by Minnesota GVHD standard risk (SR) versus high risk (HR) and plasma amphiregulin (AREG) at the onset of acute GVHD. Biology of Blood and Marrow Transplantation  , S177-S178DOI: ( /j.bbmt ) Copyright © Terms and Conditions

3 Figure 2 Overall survival and non-relapse mortality by amphiregulin (AREG)-modified Minnesota Risk Score in patients enrolled in BMT CTN 0302/0802. Biology of Blood and Marrow Transplantation  , S177-S178DOI: ( /j.bbmt ) Copyright © Terms and Conditions


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