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Brian H. Shirts, Randall W. Burt, Sean J. Mulvihill, Lisa A

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1 A Population-Based Description of Familial Clustering of Pancreatic Cancer 
Brian H. Shirts, Randall W. Burt, Sean J. Mulvihill, Lisa A. Cannon–Albright  Clinical Gastroenterology and Hepatology  Volume 8, Issue 9, Pages (September 2010) DOI: /j.cgh Copyright © 2010 AGA Institute Terms and Conditions

2 Figure 1 Distribution of the contribution to the GIF statistic by genetic distance for all pancreatic cancer cases versus 1000 sets of matched controls. Genetic distance 1 = parent/offspring, 2 = siblings, 3 = avunculars, 4 = first cousins, and so forth. Clinical Gastroenterology and Hepatology 2010 8, DOI: ( /j.cgh ) Copyright © 2010 AGA Institute Terms and Conditions

3 Figure 2 An example of Utah high-risk pancreatic adenocarcinoma pedigree. The founding male (who has 2 spouses, both shown) had a total of 4306 descendants; 6 pancreatic cancers were observed; 2.22 were expected (P = .026). Clinical Gastroenterology and Hepatology 2010 8, DOI: ( /j.cgh ) Copyright © 2010 AGA Institute Terms and Conditions


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