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E. W. Bradley, L. R. Carpio, D. F. Amanatullah, S. Kakar, L. E. Ta, M

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Presentation on theme: "E. W. Bradley, L. R. Carpio, D. F. Amanatullah, S. Kakar, L. E. Ta, M"— Presentation transcript:

1 Phlpp1 deletion increases Fgf18 expression and protects against surgically-induced osteoarthritis 
E.W. Bradley, L.R. Carpio, D.F. Amanatullah, S. Kakar, L.E. Ta, M.E. McGee-Lawrence, A.C. Newton, J.J. Westendorf  Osteoarthritis and Cartilage  Volume 23, Pages A38-A39 (April 2015) DOI: /j.joca Copyright © Terms and Conditions

2 Figure 1(A) PHLPP1 IHC in human articular cartilage from patients undergoing total joint arthroplasty for OA or FNFx. (B) OARSI scores from DMM surgeries performed on WT or Phlpp1-/- mice. (C) Fgf18 expression was determined in Phlpp1-/- cells by qPCR. (D-E) Fgf18 expression and Alcain blue staining of WT micromasses treated with the Phlpp1 inhibitor NCS *p<0.05. Osteoarthritis and Cartilage  , A38-A39DOI: ( /j.joca ) Copyright © Terms and Conditions

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