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Effect of ozone and nitrogen dioxide on the release of proinflammatory mediators from bronchial epithelial cells of nonatopic nonasthmatic subjects and.

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Presentation on theme: "Effect of ozone and nitrogen dioxide on the release of proinflammatory mediators from bronchial epithelial cells of nonatopic nonasthmatic subjects and."— Presentation transcript:

1 Effect of ozone and nitrogen dioxide on the release of proinflammatory mediators from bronchial epithelial cells of nonatopic nonasthmatic subjects and atopic asthmatic patients in vitro  Hasan Bayram, MD, PhDa, Raymond J. Sapsford, BAb, Muntasir M. Abdelaziz, PhDc, Omar A. Khair, PhDd  Journal of Allergy and Clinical Immunology  Volume 107, Issue 2, Pages (February 2001) DOI: /mai Copyright © 2001 Mosby, Inc. Terms and Conditions

2 Fig. 1 Effect of exposure for 6 hours to 10 to 100 ppb O3 on the release of IL-8 from bronchial epithelial cell cultures of nonatopic nonasthmatic subjects (A) and atopic patients with mild asthma (B) . Results are expressed as median and individual values. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2001 Mosby, Inc. Terms and Conditions

3 Fig. 2 Effect of exposure for 6 hours to 100 to 400 ppb NO2 on the release of IL-8 from bronchial epithelial cell cultures of nonatopic nonasthmatic subjects (A) and atopic patients with mild asthma (B) . Results are expressed as median and individual values. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2001 Mosby, Inc. Terms and Conditions

4 Fig. 3 Effect of exposure for 6 hours to 10 to 100 ppb O3 on the release of GM-CSF from bronchial epithelial cell cultures of nonatopic nonasthmatic subjects (A) and atopic patients with mild asthma (B) . Results are expressed as median and individual values (*P < .05 vs nonatopic nonasthmatic subjects). Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2001 Mosby, Inc. Terms and Conditions

5 Fig. 4 Effect of exposure for 6 hours to 100 to 400 ppb NO2 on the release of GM-CSF from bronchial epithelial cell cultures of nonatopic nonasthmatic subjects (A) and atopic patients with mild asthma (B) . Results are expressed as median and individual values. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2001 Mosby, Inc. Terms and Conditions

6 Fig. 5 Effect of exposure for 6 hours to 10 to 100 ppb O3 on the release of RANTES from bronchial epithelial cell cultures of atopic patients with mild asthma. Results are expressed as median and individual values. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2001 Mosby, Inc. Terms and Conditions

7 Fig. 6 Effect of exposure for 6 hours to 100 to 400 ppb NO2 on the release of RANTES from bronchial epithelial cell cultures of atopic patients with mild asthma. Results are expressed as median and individual values. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2001 Mosby, Inc. Terms and Conditions

8 Fig. 7 Effect of exposure for 6 hours to 10 to 100 ppb O3 on the release of sICAM-1 from bronchial epithelial cell cultures of nonatopic nonasthmatic subjects (A) and atopic patients with mild asthma (B) . Results are expressed as median and individual values (*P < .05 vs nonatopic nonasthmatic subjects). Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2001 Mosby, Inc. Terms and Conditions

9 Fig. 8 Effect of exposure for 6 hours to 100 to 400 ppb NO2 on the release of sICAM-1 from bronchial epithelial cell cultures of nonatopic nonasthmatic subjects (A) and atopic patients with mild asthma (B) . Results are expressed as median and individual values. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2001 Mosby, Inc. Terms and Conditions

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