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A Case of Pemetrexed-Induced Acute Lung Injury in Non-small Cell Lung Cancer  Hye Ok Kim, MD, Sung Yong Lee, MD, PhD, Jae Jeong Shim, MD, PhD, Kyung Ho.

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Presentation on theme: "A Case of Pemetrexed-Induced Acute Lung Injury in Non-small Cell Lung Cancer  Hye Ok Kim, MD, Sung Yong Lee, MD, PhD, Jae Jeong Shim, MD, PhD, Kyung Ho."— Presentation transcript:

1 A Case of Pemetrexed-Induced Acute Lung Injury in Non-small Cell Lung Cancer 
Hye Ok Kim, MD, Sung Yong Lee, MD, PhD, Jae Jeong Shim, MD, PhD, Kyung Ho Kang, MD, PhD, Bong Kyung Shin, MD, PhD  Journal of Thoracic Oncology  Volume 5, Issue 3, Pages (March 2010) DOI: /JTO.0b013e3181c5b198 Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Summary of chest computer tomography (CT) before presentation of acute lung injury (A), at presentation (B), and after some improvement (C). Journal of Thoracic Oncology 2010 5, DOI: ( /JTO.0b013e3181c5b198) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 The microscopic examination of the lung specimen revealed diffuse alveolar septal thickening by fibroblasts and scant chronic inflammatory cells, which was consistent with the features of an organizing stage of diffuse alveolar damage. Within the alveolar lumen, some remnants of hyaline membranes were observed (×100, hematoxylin and eosin [H and E]). Journal of Thoracic Oncology 2010 5, DOI: ( /JTO.0b013e3181c5b198) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

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