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Optimal Dosing Frequency of Pegylated Interferon Alfa-2b Monotherapy for Chronic Hepatitis C Virus Infection  Yoav Lurie, Regine Rouzier-Panis, George.

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Presentation on theme: "Optimal Dosing Frequency of Pegylated Interferon Alfa-2b Monotherapy for Chronic Hepatitis C Virus Infection  Yoav Lurie, Regine Rouzier-Panis, George."— Presentation transcript:

1 Optimal Dosing Frequency of Pegylated Interferon Alfa-2b Monotherapy for Chronic Hepatitis C Virus Infection  Yoav Lurie, Regine Rouzier-Panis, George J.M. Webster, Geoffrey M. Dusheiko, Mark Laughlin, Mary L. Jackson, Ran Oren  Clinical Gastroenterology and Hepatology  Volume 3, Issue 6, Pages (June 2005) DOI: /S (04) Copyright © 2005 American Gastroenterological Association Terms and Conditions

2 Figure 1 Effect of PEG-IFN-alfa2b dosage on HCV-RNA clearance at week 12. Bars are mean values with standard error (*#x002A;P < .05 vs IFN-alfa2b). BIW, 2 times/wk; QW, 1 time/wk; TIW, 3 times/wk. Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (04) ) Copyright © 2005 American Gastroenterological Association Terms and Conditions

3 Figure 2 Decrease in absolute neutrophil count (109 cells/L) by dose regimen, from treatment initiation through week 12. BIW, 2 times/wk; QW, 1 time/wk; TIW, 3 times/wk. Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (04) ) Copyright © 2005 American Gastroenterological Association Terms and Conditions


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