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Infant cardiopulmonary bypass: a procoagulant state

Published byBento Galindo Modified over 5 years ago

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Presentation on theme: "Infant cardiopulmonary bypass: a procoagulant state"— Presentation transcript:

1 Infant cardiopulmonary bypass: a procoagulant state
James J Jaggers, MD, Meg C Neal, BSN, Peter K Smith, MD, Ross M Ungerleider, MD, Jeffrey H Lawson, MD, PhD  The Annals of Thoracic Surgery  Volume 68, Issue 2, Pages (August 1999) DOI: /S (99)00644-X

2 Fig 1 Diagram of the procoagulant reactions occurring at the endothelial cell membrane level. See text for details. The Annals of Thoracic Surgery  , DOI: ( /S (99)00644-X)

3 Fig 2 Time course values of relative tissue plasminogen activator (t-PA) levels with a baseline level measured preoperatively in the operating room of 1.0. Values are displayed as the mean ± standard error of the mean. The Annals of Thoracic Surgery  , DOI: ( /S (99)00644-X)

4 Fig 3 Relative plasminogen activator inhibitor (PAI-1) levels with baseline level measured preoperatively of 1.0. Values are displayed as the mean ± standard error of the mean. The Annals of Thoracic Surgery  , DOI: ( /S (99)00644-X)

5 Fig 4 Induction of tissue factor activity on human umbilical vein endothelial cell culture when inoculated with the serum samples from the above time points. The preoperative sample is baseline and assigned a value of 1.0. Values are displayed as the mean ± standard error of the mean. The Annals of Thoracic Surgery  , DOI: ( /S (99)00644-X)

6 Fig 5 Induction of prothrombinase reaction activity on human umbilical vein endothelial cell culture when inoculated with the serum samples from the above time points. The preoperative sample is baseline and assigned a value of 1.0. Values are displayed as the mean ± standard error of the mean. The Annals of Thoracic Surgery  , DOI: ( /S (99)00644-X)

7 Fig 6 Plasma factor V levels displayed as percent of preoperative baseline value. Values represent the mean ± standard error of the mean. The Annals of Thoracic Surgery  , DOI: ( /S (99)00644-X)

8 Fig 7 Serum interleukin 1-β (IL-β) levels represented as the mean ± standard error of the mean. The Annals of Thoracic Surgery  , DOI: ( /S (99)00644-X)

9 Fig 8 Serum interleukin-6 (IL-6) levels represented as the mean ± standard error of the mean. The Annals of Thoracic Surgery  , DOI: ( /S (99)00644-X)

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