1. Repression Cell Volume 99, Issue 5, Pages 455-458 (November 1999)
Edio Maldonado, Michael Hampsey, Danny Reinberg 
Cell 
Volume 99, Issue 5, Pages (November 1999)
DOI: /S (00)

2. Figure 1
Schematic Representation of Repressor Targets during Assembly of the Transcription Initiation Complex
The factors required for each step are indicated, along with the corresponding repressors. Ssn6 and Srb10/Srb11 are shown to affect transcription at two different steps in the formation of the transcription initiation complex. One of the targets of Srb10/Srb11 is recruitment of RNAPII; however, we also speculate that Srb10/Srb11 may act at a later step by targeting TFIIH (for review, see Hampsey and Reinberg 1999). Pink barrels, nucleosomes; orange dumbbells, activator proteins; GTFs, general transcription factors. The TATA motif is illustrated by a green box.
Cell  , DOI: ( /S (00) )

3. Figure 2
Model of the Structure of the TBP-TFIIA-TFIIB-Promoter DNA Complex
The components are labeled as follows: TBP, gray; TFIIA, green; TFIIB, blue; promoter DNA, red. The model was prepared by superimposing the crystallographic structures of the TBP-TFIIB-DNA and TBP-TFIIA-DNA complexes. Residues of TBP involved in interactions with Dr1/NC2 are highlighted in orange; residues of TBP α helix 2 involved in interactions with Mot1, BRF, and TFIIA are highlighted in yellow. The structure of the TFIIA-TBP-TATA complex does not show the interaction of TFIIA with amino acid residues in TBP helix 2, although biochemical and genetic data implicate these residues in TFIIA-TBP interaction (Orphanides et al. 1996). This discrepancy might be accounted for by the absence of the central domain of the larger subunit of TFIIA in the structural studies. (The figure was generously provided by Richard H. Ebright, Rutgers University.)
Cell  , DOI: ( /S (00) )