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Effects of intracoronary shunts on coronary endothelial coating in the human beating heart  Herbert B Hangler, MD, Kristian Pfaller, PhD, Elfriede Ruttmann,

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Presentation on theme: "Effects of intracoronary shunts on coronary endothelial coating in the human beating heart  Herbert B Hangler, MD, Kristian Pfaller, PhD, Elfriede Ruttmann,"— Presentation transcript:

1 Effects of intracoronary shunts on coronary endothelial coating in the human beating heart 
Herbert B Hangler, MD, Kristian Pfaller, PhD, Elfriede Ruttmann, MD, Daniel Hoefer, MD, Thomas Schachner, MD, Guenther Laufer, MD, Herwig Antretter, MD  The Annals of Thoracic Surgery  Volume 77, Issue 3, Pages (March 2004) DOI: /j.athoracsur

2 Fig 1 (A) Control specimen from patient 2; scanning electron micrograph depicts an overview of a coronary artery cut into half longitudinally after pressure fixation with an intact endothelial surface. (B) Inset, higher magnification with tight endothelial cell attachment completely covering the vascular surface, corresponding to a grade 0 classification. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )

3 Fig 2 (A) Dehiscent intercellular junctions and detachment of endothelial cells (grade 2: minor endothelial injury). (B) Inset, higher magnification. (# = endothelial cell.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )

4 Fig 3 (A) Focal endothelial denudation after vessel loop occlusion. Note denuded area (*), with subendothelial tissue exposed (grade 3). (# = remnant endothelial cells.) (B) Inset, higher magnification. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )

5 Fig 4 (A) Severe endothelial injury (grade 4) after shunt (outer diameter, 2.5 mm) insertion in vessel from patient 2. Note denuded area (*), with subendothelial tissue exposed. (# = remnant endothelial cells.) (B) Inset, higher magnification. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )


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