1. Volume 93, Issue 6, Pages 909-912 (June 1998)
The Fruit Fly: A Model Organism to Study the Genetics of Alcohol Abuse and Addiction? 
Hugo J Bellen 
Cell 
Volume 93, Issue 6, Pages (June 1998)
DOI: /S (00)

2. Figure 1 Signaling Components Affecting the cAMP Pathway
A comparison of the molecular components of the cAMP pathway that have been implicated in acute and chronic ethanol responses in vertebrate cultured neurons, and alcohol sensitivity in Drosophila. Acute alcohol exposure up-regulates the cAMP signaling pathway. However, not all cells may respond in a similar fashion. The genes studied by Moore et al are highlighted in blue.
Cell  , DOI: ( /S (00) )

3. Figure 2 The Inebriometer
The apparatus in this cartoon consists of a tank filled with ethanol that is perfused with air. The ethanol vapor is mixed with air to obtain the desired concentration of ethanol vapor. This mixture of ethanol and air flows through a column with plastic baffles. Unanesthetized flies are poured into the top of the column. The flies can hold on to the baffles until they are too inebriated, upon which they fall down and elute out of the column. The mean elution time (MET) varies between 10 and 32 min, depending on the mutant strain or if the fly strain has been selected for ethanol resistance.
Cell  , DOI: ( /S (00) )