1. Noninvasive Assessment of Brain Injury in a Canine Model of Hypothermic Circulatory Arrest Using Magnetic Resonance Spectroscopy 
Christopher J. Barreiro, MD, Jason A. Williams, MD, Torin P. Fitton, MD, Mary S. Lange, MA, Mary E. Blue, PhD, Lisa Kratz, PhD, Peter B. Barker, PhD, Mahaveer Degaonkar, PhD, Vincent L. Gott, MD, Juan C. Troncoso, MD, Michael V. Johnston, MD, William A. Baumgartner, MD 
The Annals of Thoracic Surgery 
Volume 81, Issue 5, Pages (May 2006)
DOI: /j.athoracsur
Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

2. Fig 1
Clinical neurologic scores using the Pittsburgh canine neurologic scoring system (0 = normal; 500 = brain death). (Dark gray bars = hypothermic circulatory arrest [n = 16]; light gray bars = hypothermic circulatory arrest plus diazoxide [n = 23]; hr = hours.)
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

3. Fig 2
Magnetic resonance spectroscopy–measured N-acetyl-asparate:choline (NAA:Cho) ratios for the cortex, cerebellum, and hippocampus. The p values compare normal animals (black bars; n = 15) versus hypothermic circulatory arrest (HCA) animals (dark gray bars; n = 15); *p values compare HCA versus HCA+diazoxide animals (light gray bars; n = 15). (NS = not significant.)
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

4. Fig 3
Fresh brain tissue N-acetyl-asparate extraction determined by mass spectrometry for the cortex, cerebellum, and hippocampus. The p values compare normal animals (black bars; n = 15) versus 24-hour hypothermic circulatory arrest (HCA) animals (dark gray bars; n = 15); *p values compare HCA versus 24-hour HCA+diazoxide animals (light gray bars; n = 15).
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions