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Meta-analysis: is moving the goal post the answer?

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Presentation on theme: "Meta-analysis: is moving the goal post the answer?"— Presentation transcript:

1 Meta-analysis: is moving the goal post the answer?
Matthias Egger, George Davey Smith, Jonathan AC Sterne  The Lancet  Volume 351, Issue 9114, (May 1998) DOI: /S (05) Copyright © 1998 Elsevier Ltd Terms and Conditions

2 Cumulative meta-analysis of trials of intravenous magnesium for suspected myocardial infarction, with stopping boundaries (2α=0·01) Analysis of ten selected trials reported by Pogue and Yusuf1 (upper panel)and re-analysis with all 15 trials (lower panel). Trial 11 is ISIS-4. References 1–16 available from authors. The Lancet  , DOI: ( /S (05) ) Copyright © 1998 Elsevier Ltd Terms and Conditions


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