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Inside Out: Bone Marrow Necrosis and Fat Embolism Complicating Sickle-β+ Thalassemia  Jori May, MD, Joseph C. Sullivan, MD, Daniel LaVie, MD, Katherine.

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Presentation on theme: "Inside Out: Bone Marrow Necrosis and Fat Embolism Complicating Sickle-β+ Thalassemia  Jori May, MD, Joseph C. Sullivan, MD, Daniel LaVie, MD, Katherine."— Presentation transcript:

1 Inside Out: Bone Marrow Necrosis and Fat Embolism Complicating Sickle-β+ Thalassemia 
Jori May, MD, Joseph C. Sullivan, MD, Daniel LaVie, MD, Katherine LaVie, MD, Marisa B. Marques, MD  The American Journal of Medicine  Volume 129, Issue 12, Pages e321-e324 (December 2016) DOI: /j.amjmed Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Magnetic resonance imaging obtained on day 1. (A) Diffusion-weighted image revealed innumerable punctate foci with concordant decreased signal on apparent diffusion coefficient maps (not shown) not conforming to a typical vascular territory, referred to as a “starfield” appearance. (B) Fluid attenuation inversion recovery demonstrated moderate concordance, indicating a subacute pattern mixed with other chronic white matter changes. The American Journal of Medicine  , e321-e324DOI: ( /j.amjmed ) Copyright © 2016 Elsevier Inc. Terms and Conditions

3 Figure 2 Reconstruction images from CT of the abdomen and pelvis show femoral head osteonecrosis. The American Journal of Medicine  , e321-e324DOI: ( /j.amjmed ) Copyright © 2016 Elsevier Inc. Terms and Conditions

4 Figure 3 Platelet count and renal recovery after exchange transfusion.
The American Journal of Medicine  , e321-e324DOI: ( /j.amjmed ) Copyright © 2016 Elsevier Inc. Terms and Conditions


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