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Familial hypertryptasemia with associated mast cell activation syndrome  Vito Sabato, MD, Els Van De Vijver, MD, PhD, Margo Hagendorens, MD, PhD, Inge.

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Presentation on theme: "Familial hypertryptasemia with associated mast cell activation syndrome  Vito Sabato, MD, Els Van De Vijver, MD, PhD, Margo Hagendorens, MD, PhD, Inge."— Presentation transcript:

1 Familial hypertryptasemia with associated mast cell activation syndrome 
Vito Sabato, MD, Els Van De Vijver, MD, PhD, Margo Hagendorens, MD, PhD, Inge Vrelust, MD, Edwin Reyniers, MD, PhD, Erik Fransen, MD, PhD, Chris Bridts, MLT, Luc De Clerck, MD, PhD, Geert Mortier, MD, PhD, Peter Valent, MD, PhD, Didier Ebo, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 134, Issue 6, Pages e3 (December 2014) DOI: /j.jaci Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 A, Measurements of serum tryptase levels in the asymptomatic phase and during gastrointestinal symptoms in one family member (subject II-5). From these measurements, it is evident an elevated basal tryptase level (constantly >20 ng/mL) and a significant increase (>20% of baseline plus 2 ng/mL) in concomitance of symptoms. B, Genealogical tree indicating familial occurrence of MCA/hypertryptasemia and showing a pattern compatible with dominant inheritance. Journal of Allergy and Clinical Immunology  , e3DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

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