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Biomarkers: A Basic Glossary

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Presentation on theme: "Biomarkers: A Basic Glossary"— Presentation transcript:

1 Biomarkers: A Basic Glossary
Ramachandran S. Vasan. Circulation 2006;113:

2 Desirable Features of Biomarkers of Atherosclerotic CVD
R. S. Vasan. Circulation 2006;113:

3 Measures of biomarker test performance
Ramachandran S. Vasan. Circulation 2006;113:

4 Approaches to defining “abnormal” biomarker values
FN indicates false-negative; FP, false-positive; TN, true-negative; TP, true-positive; Pts, patients; and F/U, follow-up Ramachandran S. Vasan. Circulation 2006;113:

5 Sources of Biomarker Variability
R. S. Vasan. Circulation 2006;113:

6 Techniques Available for Biomarker Development
Ramachandran S. Vasan. Circulation 2006;113:

7 Brief “Omics” Glossary
R. S. Vasan. Circulation 2006;113:

8 Glossary of Terms for Select Techniques Used in the OMICs Toolbox
R. S. Vasan. Circulation 2006;113:

9 Five phases of biomarker development: from discovery to delivery
Ramachandran S. Vasan. Circulation 2006;113:

10 Some Key Questions to Ask Before Using a New Biomarker in Practice
Ramachandran S. Vasan. Circulation 2006;113:

11 Biomarkers for Identifying the Vulnerable Patient
R. S. Vasan. Circulation 2006;113:

12 Biomarkers of acute coronary syndromes
Ramachandran S. Vasan. Circulation 2006;113:

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