1. A myriad of responses The Lancet Volume 358, (December 2001)
Charles T Esmon, PhD 
The Lancet 
Volume 358, (December 2001)
DOI: /S (01)
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2. Figure
Severe sepsis induces release of cytokines, oxidants, and proteases from leucocytes, injuring the vessel, triggering clotting, and inhibiting the protein C pathway (A). APC limits many of these events, protecting the vessels and organs from injury (B).
The Lancet  , DOI: ( /S (01) )
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3. The Lancet 2001 358, DOI: (10.1016/S0140-6736(01)07073-8)
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